T3 should be taken once a day in the morning
Clen is broken into 2 doses, except in the first week when it is not needed as there is only one dose. Clen should be taken no later than 5pm so it does not affect sleep. Doses should be a few hours apart. Although individual tolerance needs to assessed, this is a good place to start.

Week One – 12.5 mcg T3, 0.04mg Clen. daily
Week Two – 25 mcg T3, 0.04mg Clen. twice daily
Week Three – 50 mcg T3 – Off of Clen. for this week – Add 2 (25mg/ tab Diphenhydramine HCl)
at betime
Week Four – 75 mcg T3 – 0.04mg Clen. twice daily – Keep 2 (25mg/ tab Diphenhydramine HCl)
at bedtime

Stop Clen and Taper down T3: 75mcg for 4 days, 50mcg for 4 days, 25 mcg for 4 days, 12.5 mcg for 4 days
Never take more than 200 mcg Clen. Dyphenhydramine is added in the off week at bedtime and the first week back on Clen to increase receptor uptake and increase the effectiveness of the Clen.